{"id":220,"date":"2023-05-12T16:20:13","date_gmt":"2023-05-12T20:20:13","guid":{"rendered":"https:\/\/thritatech.com\/?page_id=220"},"modified":"2023-05-19T17:55:52","modified_gmt":"2023-05-19T21:55:52","slug":"analysis-example","status":"publish","type":"page","link":"https:\/\/thrita.tech\/index.php\/analysis-example\/","title":{"rendered":"Personalized Brain Analysis"},"content":{"rendered":"\n<p><br>This page provides insights into the capability of the Personalized Brain (PB) technology for analyzing brain information. Please note that the PB is still in development, and a comprehensive analysis will be provided in the future.<\/p>\n\n\n\n<p>We used three datasets: T1-MRI mapping and fMRI mapping for three subjects\u2014 one with Alzheimer&#8217;s Disease (AD), one with Mild Cognitive Impairment (MCI), and one Normal Control Subject (NCS). Since we focused on fMRI mapping, our analysis only considers short-range connectivity between neurons while excluding long connectivity and high-frequency neural activities.<\/p>\n\n\n\n<p>In the initial stage, we constructed the PB&#8217;s structure based on T1-weighted mapping. Subsequently, we utilized fMRI mapping to obtain short-range functional connectivity within the PB.<\/p>\n\n\n\n<p>For our analysis, we conducted in vivo simulations by briefly stimulating the cingulate gyrus in PB while keeping the rest of the brain silent. We recorded the response to observe how functional activity spreads across the brain in the following moments. The figure below illustrates the average functional activity in PB during this test. The figure displays a horizontal slice of PB, and you can select different slices using the slide bar at the bottom.<\/p>\n\n\n<style>\n       .errordiv { padding:10px; margin:10px; border: 1px solid #555555;color: #000000;background-color: #f8f8f8; width:500px; }#advanced_iframe {visibility:visible;opacity:1;vertical-align:top;}.ai-info-bottom-iframe { position: fixed; z-index: 10000; bottom:0; left: 0; margin: 0px; text-align: center; width: 100%; background-color: #ff9999; padding-left: 5px;padding-bottom: 5px; border-top: 1px solid #aaa } a.ai-bold {font-weight: bold;}#ai-layer-div-advanced_iframe p {height:100%;margin:0;padding:0}<\/style><script type=\"text\/javascript\">var ai_iframe_width_advanced_iframe = 0;var ai_iframe_height_advanced_iframe = 0;function aiReceiveMessageadvanced_iframe(event) {  aiProcessMessage(event,\"advanced_iframe\", \"true\",\"\",\"false\",\"false\");}if (window.addEventListener) {  window.addEventListener(\"message\", aiReceiveMessageadvanced_iframe);} else if (el.attachEvent)  {  el.attachEvent(\"message\", aiReceiveMessageadvanced_iframe);}var aiOnloadScrollTop=\"true\";var aiShowDebug=false;\n\t\tif (typeof aiReadyCallbacks === 'undefined') {\n\t\t\tvar aiReadyCallbacks = [];\n\t\t} else if (!(aiReadyCallbacks instanceof Array)) {\n\t\t\tvar aiReadyCallbacks = [];\n\t\t}    function aiShowIframeId(id_iframe) { jQuery(\"#\"+id_iframe).css(\"visibility\", \"visible\");    }    function aiResizeIframeHeight(height) { aiResizeIframeHeight(height,advanced_iframe); }    function aiResizeIframeHeightId(height,width,id) {aiResizeIframeHeightById(id,height);}<\/script><iframe id=\"advanced_iframe\"  name=\"advanced_iframe\"  src=\"https:\/\/thrita.tech\/wp-content\/uploads\/2023\/05\/Analysis_fig1.html\"  width=\"100%\"  height=\"600\"  frameborder=\"0\"  border=\"0\"  allowtransparency=\"true\"  loading=\"lazy\"  style=\";border-width: 0px;;border: none;;width:100%;;height:600px;\" ><\/iframe><script type=\"text\/javascript\">var ifrm_advanced_iframe = document.getElementById(\"advanced_iframe\");var hiddenTabsDoneadvanced_iframe = false;\nfunction resizeCallbackadvanced_iframe() {}<\/script><script type=\"text\/javascript\"><\/script><p style=\"display:block !important; visibility:visible !important;margin: -18px 14px 0 0;padding-left: 3px;padding-top:3px;background: white; overflow: hidden; position: relative; line-height:15px;width: fit-content;\"><small style=\"display:block !important;visibility:visible !important\">powered by Advanced iFrame<\/small><\/p>\n\n\n<p>To deepen our understanding, we calculated the response of different parts of PB to cingulate gyrus stimulation. The following figure demonstrates the synchronization of neural activity in other PB regions in relation to the cingulate gyrus. This figure presents data for the three subjects: AD, MCI, and NCS. The figure is interactive, allowing you to toggle the results for AD, NCS, and MCI subjects on or off.<\/p>\n\n\n<style>\n       .errordiv { padding:10px; margin:10px; border: 1px solid #555555;color: #000000;background-color: #f8f8f8; width:500px; }#advanced_iframe_2 {visibility:visible;opacity:1;vertical-align:top;}.ai-info-bottom-iframe { position: fixed; z-index: 10000; bottom:0; left: 0; margin: 0px; text-align: center; width: 100%; background-color: #ff9999; padding-left: 5px;padding-bottom: 5px; border-top: 1px solid #aaa } a.ai-bold {font-weight: bold;}#ai-layer-div-advanced_iframe_2 p {height:100%;margin:0;padding:0}<\/style><script type=\"text\/javascript\">var ai_iframe_width_advanced_iframe_2 = 0;var ai_iframe_height_advanced_iframe_2 = 0;function aiReceiveMessageadvanced_iframe_2(event) {  aiProcessMessage(event,\"advanced_iframe_2\", \"true\",\"\",\"false\",\"false\");}if (window.addEventListener) {  window.addEventListener(\"message\", aiReceiveMessageadvanced_iframe_2);} else if (el.attachEvent)  {  el.attachEvent(\"message\", aiReceiveMessageadvanced_iframe_2);}var aiOnloadScrollTop=\"true\";var aiShowDebug=false;\n\t\tif (typeof aiReadyCallbacks === 'undefined') {\n\t\t\tvar aiReadyCallbacks = [];\n\t\t} else if (!(aiReadyCallbacks instanceof Array)) {\n\t\t\tvar aiReadyCallbacks = [];\n\t\t}    function aiShowIframeId(id_iframe) { jQuery(\"#\"+id_iframe).css(\"visibility\", \"visible\");    }    function aiResizeIframeHeight(height) { aiResizeIframeHeight(height,advanced_iframe_2); }    function aiResizeIframeHeightId(height,width,id) {aiResizeIframeHeightById(id,height);}<\/script><iframe id=\"advanced_iframe_2\"  name=\"advanced_iframe_2\"  src=\"https:\/\/thrita.tech\/wp-content\/uploads\/2023\/05\/Analysis_Comparison.html\"  width=\"100%\"  height=\"600\"  frameborder=\"0\"  border=\"0\"  allowtransparency=\"true\"  loading=\"lazy\"  style=\";border-width: 0px;;border: none;;width:100%;;height:600px;\" ><\/iframe><script type=\"text\/javascript\">var ifrm_advanced_iframe_2 = document.getElementById(\"advanced_iframe_2\");var hiddenTabsDoneadvanced_iframe_2 = false;\nfunction resizeCallbackadvanced_iframe_2() {}<\/script><script type=\"text\/javascript\"><\/script><p style=\"display:block !important; visibility:visible !important;margin: -18px 14px 0 0;padding-left: 3px;padding-top:3px;background: white; overflow: hidden; position: relative; line-height:15px;width: fit-content;\"><small style=\"display:block !important;visibility:visible !important\">powered by Advanced iFrame<\/small><\/p>","protected":false},"excerpt":{"rendered":"<p>This page provides insights into the capability of the Personalized Brain (PB) technology for analyzing brain information. Please note that the PB is still in development, and a comprehensive analysis will be provided in the future. We used three datasets: T1-MRI mapping and fMRI mapping for three subjects\u2014 one with Alzheimer&#8217;s Disease (AD), one with &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/thrita.tech\/index.php\/analysis-example\/\" class=\"more-link\">Read more<span class=\"screen-reader-text\"> &#8220;Personalized Brain Analysis&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inspiro_hide_title":false,"footnotes":""},"class_list":["post-220","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/thrita.tech\/index.php\/wp-json\/wp\/v2\/pages\/220","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/thrita.tech\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/thrita.tech\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/thrita.tech\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/thrita.tech\/index.php\/wp-json\/wp\/v2\/comments?post=220"}],"version-history":[{"count":6,"href":"https:\/\/thrita.tech\/index.php\/wp-json\/wp\/v2\/pages\/220\/revisions"}],"predecessor-version":[{"id":412,"href":"https:\/\/thrita.tech\/index.php\/wp-json\/wp\/v2\/pages\/220\/revisions\/412"}],"wp:attachment":[{"href":"https:\/\/thrita.tech\/index.php\/wp-json\/wp\/v2\/media?parent=220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}